Research Neuroinflammation Brain Repair


Neuroinflammation & Brain Repair β€” Research Dashboard

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Anti inflammatory
BBB repair
Adaptogen
Detox
Oxygenation
Circulatory
Immunomodulator

Root causes of brain inflammation tap to collapse

Infection induced

Mechanism: Immune activation, cytokine surge, microglial overdrive
Examples: Flu, COVID, pneumonia, meningitis
Note: Secondary neuroinflammation can follow the acute illness
Inflammation

Autoimmune and molecular mimicry

Mechanism: Antibodies cross react with neural tissue
Examples: Post viral autoimmune encephalitis
Note: Can manifest as confusion, brain fog
Autoimmune

Toxic and metabolic

Mechanism: Oxidative stress, mitochondrial strain
Examples: Heavy metals, mycotoxins, ammonia
Note: Detox and antioxidant support often indicated
Detox

Vascular and barrier breakdown

Mechanism: Leaky endothelium, barrier permeability
Examples: Hypertension, trauma
Note: Tight junction support and microvascular tone
BBB repairCirculatory

Oxygen deficiency

Mechanism: Hypoxia, ROS rise, ATP drop
Examples: Pneumonia, anemia
Note: Neurons are highly oxygen sensitive
Oxygenation

Gut brain axis

Mechanism: Endotoxin leakage raises cytokines
Examples: Dysbiosis, barrier compromise
Note: Microbiome balance can calm systemic signals
Gut

Mechanistic focus and example herbs tap to collapse

Focus area Cellular mechanism Support type Example herbs Notes
Reduce inflammation Lower NFkB and cytokines, calm microglia Anti inflammatory, adaptogenic Boswellia, Turmeric, Tulsi, Ginger neuro calming
Protect and repair cells Antioxidants limit ROS; mitochondrial support Antioxidant, adaptogen Jiaogulan, Rhodiola, Gotu Kola, Ashwagandha resilience
Repair barrier integrity Strengthen tight junctions; endothelial tone Vascular, astringent Gotu Kola, Witch Hazel, Hawthorn targeted
Enhance oxygen delivery Microcirculation, RBC efficiency Circulatory stimulant Ginkgo, Cayenne, Beetroot perfusion
Modulate immune activity Balance Th1 Th2; tone microglia Immunomodulator Astragalus, Reishi, Licorice* *licorice with caution for BP
Remove neurotoxins Bind and escort metals and toxins Detoxifier Cilantro + Chlorella, Zeolite, Bentonite gentle pace

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Targeted herbs and mechanisms tap to collapse

Boswellia serrata

Primary action: Anti inflammatory
Mechanism: 5 lipoxygenase pathway moderation
Brain impact: Edema and myelin comfort
Anti inflammatory

Tulsi

Primary action: Adaptogen
Mechanism: Cortisol balance, antioxidant tone
Brain impact: Calmer oxidative load
Adaptogen

Jiaogulan

Primary action: Antioxidant circulatory
Mechanism: SOD support and nitric oxide
Brain impact: Better perfusion
CirculatoryOxygenation

Gotu Kola

Primary action: Vascular repair
Mechanism: Collagen synthesis, capillary tone
Brain impact: Barrier support
BBB repair

Witch Hazel

Primary action: Astringent
Mechanism: Tannins support capillary seal
Brain impact: Permeability tempering
BBB repair

Turmeric

Primary action: Anti inflammatory
Mechanism: COX pathway balance, TNF tone
Brain impact: Neuron comfort
Anti inflammatory

Reishi

Primary action: Immunomodulator
Mechanism: Beta glucan pattern training
Brain impact: Calmer microglia tone
Immunomodulator

Cilantro + Chlorella

Primary action: Metal escort
Mechanism: Chelation and binding
Brain impact: Lower neurotoxic burden
Detox

Ginkgo

Primary action: Microcirculation
Mechanism: Platelet and vascular tone balance
Brain impact: Oxygen delivery
Circulatory

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Educational information only; not a substitute for medical advice, diagnosis or treatment.

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